Fagonia Cretica Tea Buy

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Background: Plants have proved to be an important source of anti-cancer drugs. Here we have investigated the cytotoxic action of an aqueous extract of Fagonia cretica, used widely as a herbal tea-based treatment for breast cancer.

Conclusions/significance: Our results demonstrate for the first time that an aqueous extract of Fagonia cretica can induce cell cycle arrest and apoptosis via p53-dependent and independent mechanisms, with activation of the DNA damage response. We also show that FOXO3a is required for activity in the absence of p53. Our findings indicate that Fagonia cretica aqueous extract contains potential anti-cancer agents acting either singly or in combination against breast cancer cell proliferation via DNA damage-induced FOXO3a and p53 expression.

Please do share with regards Age and illness Details of patient in our email ( AsmiConsultancyHerbals@gmail.com ) so we can confirm on Medically recommended Dosage of Organic Fagonia cretica Tea. Because in an early stage of Cancer, the mixing ratio with regards Organic Fagonia cretica is Leaf 40 : Flower 60 while in Stage 4 / Terminal illness, its Leaf 10 : Flower 90 and similarly as per illness severity / type of carcinoma, the mixing ratio of Leaf : Flower and daily intake dosage also varies. We shall also Prescribe other recommended Medicinal Herbs and share all details on Diet Regulations, Lifestyle Regimen, Costing, Disptach and the order can be easily confirmed through PayPal / Transfer Wise / Bank Transfer / Western Union Money Transfer / Money Gram. IMPORTANT : Its hereby requested you buy Fagonia (cretica) indica Tea only from an Authenticated Source because as per Ayurveda Literature there are certain very important recommendations mentioned in RAS SHASHTRA which must be followed in the process of Drying, Ratio Maintenance (Leaf : Flower : Bark) and Powdering of Fagonia (cretica) indica. Our Hospital - Asmi Ayurveda Consultancy and Herbals has been awarded with \"Registered Trade Mark\" of Organic FAGONIA CRETICA TEA as we have been following the most stringent of protocols for our product and also we have been sourcing the authenticated product from verified cultivators. We have been doing our tasks and working with patients of Cancer with complete honesty in our efforts and its now a success which belongs to each patient of ours for their trust in our Medical Services. Registrar of Trademarks, Govt of India after analyzing all our protocols, documentation and product gave the verdict in our favor and thus its now a huge boost for all our patients as the Organic Fagonia cretica Tea / VIRGIN'S MANTLE TEA which we are providing is Certified Authentic and Organic, so absolutely safe to use and also high in Medicinal Benefits. Herbal Treatment for Cancer Patients Alternative Treatment for Cancer Patients

Fagonia Cretica - As per illness, severity / stage of Carcinoma, varied mixing ratios with regards Leaf : Flower : Stem are used. The prime action of Organic Fagonia cretica shall be to initiate cell cycle arrest on the energy center of cancer DNA and thus enable remission in metastatic tendencies. Fagonia cretica induces cell cycle arrest and apoptosis via p53-dependent and independent mechanisms, with activation of the DNA damage response.

We are hereby providing a graphical display of the list of countries where we have successfully dispatched our Shipment of Fagonia (cretica) indica Tea through DHL Express Cargo Service with committment and a definite time frame. We always provide our Patients with the Waybill of the Parcel, so that the movement of Parel can be tracked on Official Website of DHL. Through DHL, the patient gets regular updates in his / her email id regarding the movement of Parcel and also the Parcel is received at the destination in a maximum of 3-5 working days from the date of dispatch.

DISPATCH DETAILS of Organic Fagonia (cretica) indica Tea / Virgin's Mantle Tea Details of Dispatching Medicine Parcel to your Address anywhere in the World through DHL EXPRESS CARGO SERVICE

Please do share with regards Age and illness details of patient in our email ( AsmiConsultancyHerbals@gmail.com ) so we can confirm the details on Medically recommended intake Dosage of Organic Fagonia cretica Tea. Because in an early case of Cancer, the mixing ratio with regards Organic Fagonia cretica is Leaf 40 : Flower 60 while in Stage 4 / Terminal illness, its Leaf 10 : Flower 90 and similarly as per illness severity / type of carcinoma, the mixing ratio of Leaf : Flower and daily intake dosage also varies.

Results demonstrate for the first time that an aqueous extract of Fagonia (cretica) indica can induce cell cycle arrest and apoptosis via p53-dependent and independent mechanisms, with activation of the DNA damage response. We also show that FOXO3a is required for activity in the absence of p53. Our findings indicate that Fagonia (cretica) indica aqueous extract contains potential anti-cancer agents acting either singly or in combination against cancer cell proliferation via DNA damage-induced FOXO3a and p53 expression.

Fagonia cretica is a species of plant in the caltrop family (Zygophyllaceae). It is native to dry regions of the Mediterranean Basin in North Africa (in Cape Verde, Canary Islands, Morocco, Algeria, Tunisia, Libya and Egypt), Southern Europe (in the Balearic Islands, Portugal, Southeast Spain, Sicily, and Greece) and West Asia (in Saudi Arabia and the Sinai peninsula).[1]

Morphology of Fagonia cretica:Duralabha is a small shrub having thorns, growing to a height of 1-3 feet in the dry regions of western India. The small branches are thick and have nodules in them. The leaves are shrunken and have 3-4 leaflets in it. The thorns present in the plant are thick and strong. Flowers are pale red in color and are seen just before winter. The fruits have hairy structure, having edges and bent in structure.

Fagonia cretica chemical composition:The aerial parts contain several tri- terpenoid saponins which gave sapogenin, nahagenin, oleanolic acid. Aerial parts also gave diterpenes, fagonone and its derivatives, besides ﬂavonoids. The fruits are rich in ascorbic acid.

Research articles related to Fagonia cretica:Hepato- protective action: The present study was designed to assess the hepatoprotective activity and cytotoxicity of methanolic and water extracts of F. cretica L. These extracts were studied for their hepatoprotective activity using CCl4 induced liver damage in wistar albino rats. The methanolic and water extracts of F. cretica L. at oral dose of (400 mg/kg) showed highly significant (p

Anti- cancerous action: An aqueous extract of Fagonia cretica was able to reduce cell viability significantly in two phenotypically different breast cancer cell lines (MCF-7 and MDA-MB-231). This activity was markedly reduced in normal mammary epithelial cells (HMEpC).Further investigation into the mode of action revealed that extract treatment induced cell cycle arrest and apoptosis in both MCF-7 and MDA-MB-231 cell lines.

The plant, Fagonia cretica, and known as Virgon's Mantlem, is commonly used in herbal tea. It has been traditionally used to treat women in rural Pakistan who have breast cancer, but up until now this treatment has been regarded as something of a folklore remedy. However, patients in Pakistan who have taken the plant extract have reported that it does not appear to generate any of the serious common side effects associated with other cancer treatments, such as loss of hair, drop in blood count or diarrhea.

The use of whole plant extracts originates from nature's wisdom to target one or more cellular signaling pathways to prevent the spread of multiple drug resistance caused by the heterogeneity of cancer cells8,9. Plants polyphenols being major antioxidant and anticancer agent works to treat various inflammatory diseases10,11,12. The in vivo action of polyphenol is generally limited by their low stability, bioavailability, and cellular absorption13,14. Aqueous extracts of Fagonia cretica L. have been reported to induce cell cycle arrest and apoptosis in vitro. The mechanistic involvement of p53-dependent and independent pathways and activation of the DNA damage response were identified for cell proliferation inhibition and natural cell death15.

The present study is designed for efficient delivery of F. cretica L. plant extract based albumin, liposomes and silver nanoparticles for in vitro anticancer potential against MCF-7, Hep-2 and HUH-7 cancer cell lines along with the plant nanoparticles based treatment dependent transcriptional level expression modulation of apoptotic pathway associated genes TRAIL, DR4, DR5, FADD and TP53 as natural cell death mechanism induction therapeutic option for cancer.

Fagonia cretica, belonging to peripheral northern region of Pakistan, was collected and used in the present study as per guidelines and permission approved by the Department of Botany, PMAS-Arid Agriculture University Rawalpindi (PMAS-AAUR), Pakistan. Dr. Rahmatullah Qureshi, a renowned botanist at the university identified the plant. A voucher specimen of the plant (PMAS-06) has been deposited in the public herbarium at PMAS-AAUR, a public sector institution. Dr. Rahmatullah Qureshi (PhD), a renowned botanist at the university identified the plant. 59ce067264

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